Membrane Composition and Raf[CRD]-Membrane Attachment Are Driving Forces for K-Ras4B Dimer Stability-Reference-Cited by-同舟云学术

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Membrane Composition and Raf[CRD]-Membrane Attachment Are Driving Forces for K-Ras4B Dimer Stability

Published:2022-02-10 Issue:7 Volume:126 Page:1504-1519
ISSN:1520-6106
Container-title:The Journal of Physical Chemistry B
language:en
Short-container-title:J. Phys. Chem. B

Author:

Andreadelis Ioannis¹,Kiriakidi Sofia¹,Lamprakis Christos¹,Theodoropoulou Anastasia¹,Doerr Stefan¹^ORCID,Chatzigoulas Alexios¹,Manchester John²,Velez-Vega Camilo²,Duca José S.²,Cournia Zoe¹^ORCID

Affiliation:

1. Biomedical Research Foundation, Academy of Athens, 4 Soranou Ephessiou, 11527 Athens, Greece

2. Computer-Aided Drug Discovery, Global Discovery Chemistry, Novartis Institutes for BioMedical Research, 100 Technology Square, Cambridge, Massachusetts 02139, United States

Funder

Hellenic Foundation for Research and Innovation

Publisher

American Chemical Society (ACS)

Subject

Materials Chemistry,Surfaces, Coatings and Films,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jpcb.1c01184

Reference64 articles.

1. The Guanine Nucleotide-Binding Switch in Three Dimensions

2. GEFs and GAPs: Critical Elements in the Control of Small G Proteins

3. A Comprehensive Survey of Ras Mutations in Cancer

4. Drugging the undruggable RAS: Mission Possible?

5. Structure-Function Relationships of the G Domain, a Canonical Switch Motif

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1. Molecular dynamics simulations for the structure-based drug design: targeting small-GTPases proteins;Expert Opinion on Drug Discovery;2024-08-06

2. Membrane-Driven Dimerization of the Peripheral Membrane Protein KRAS: Implications for Downstream Signaling;International Journal of Molecular Sciences;2024-02-21

3. Structural insights into the complex of oncogenic KRas4B^G12Vand Rgl2, a RalA/B activator;Life Science Alliance;2023-10-13

4. Structural insights into the complex of oncogenic K-Ras4B^G12Vand Rgl2, a RalA/B activator;2022-10-10

5. Evaluation of K-Ras4B dimer interfaces and the role of Raf effectors;2022-10-04

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