1. Department of Biomedical Engineering, National Cheng Kung University, No.1, University Road, Tainan 701, Taiwan
2. Medical Device Innovation Center, National Cheng Kung University, No.1 University Road, Tainan 701, Taiwan
3. Department of Electrical Engineering, National Cheng Kung University, No.1, University Road, Tainan 701, Taiwan
4. Department of Information Management, National University of Kaohsiung, Kaohsiung University Rd, Kaohsiung 811, Taiwan
5. Department of Mathematics, University of Taipei, No.1, Ai-Guo West Road, Taipei 100234, Taiwan
6. Center for Molecular Medicine and Genetics, Wayne State University, School of Medicine, Detroit, Michigan 48201, United States