Discovery of a Novel Macrocyclic ATP Citrate Lyase Inhibitor
Author:
Affiliation:
1. Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease and State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, P. R. China
Funder
Natural Science Foundation of Jiangsu Province
National Natural Science Foundation of China
Publisher
American Chemical Society (ACS)
Subject
Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jcim.2c00345
Reference33 articles.
1. Regulation and Metabolic Significance of De Novo Lipogenesis in Adipose Tissues
2. De novo lipogenesis in health and disease
3. The vital role of ATP citrate lyase in chronic diseases
4. The Lipogenesis Pathway as a Cancer Target
5. Deficiency in hepatic ATP-citrate lyase affects VLDL-triglyceride mobilization and liver fatty acid composition in mice
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