Low Inhibiting Power of N···CO Based Peptidomimetic Compounds against HIV-1 Protease: Insights from a QM/MM Study-Reference-Cited by-同舟云学术

Low Inhibiting Power of N···CO Based Peptidomimetic Compounds against HIV-1 Protease: Insights from a QM/MM Study

Published:2010-03-26 Issue:4 Volume:6 Page:1369-1379
ISSN:1549-9618
Container-title:Journal of Chemical Theory and Computation
language:en
Short-container-title:J. Chem. Theory Comput.

Author:

Garrec Julian¹,Cascella Michele¹,Rothlisberger Ursula¹,Fleurat-Lessard Paul¹

Affiliation:

1. Université de Lyon, École Normale Supérieure de Lyon, Laboratoire de Chimie − UMR 5182, 46 allée d’Italie, 69364 Lyon Cedex 07, France, Department of Chemistry and Biochemistry, University of Bern, Freiestrasse 3, CH-3012 Bern, Switzerland, and Laboratory of Computational Chemistry and Biochemistry, Institute of Chemical Sciences and Engineering, École Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland

Publisher

American Chemical Society (ACS)

Subject

Physical and Theoretical Chemistry,Computer Science Applications

Link

https://pubs.acs.org/doi/pdf/10.1021/ct9004728

Reference84 articles.

1. INHIBITORS OF HIV-1 PROTEASE: A Major Success of Structure-Assisted Drug Design

2. STRUCTURE-BASED INHIBITORS OF HIV-1 PROTEASE

3. Human immunodeficiency virus protease expressed in Escherichia coli exhibits autoprocessing and specific maturation of the gag precursor.

4. Structure and Function of Retroviral Proteases

5. A cumulative specificity model for proteases from human immunodeficiency virus types 1 and 2, inferred from statistical analysis of an extended substrate data base

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