Dopamine/Serotonin Receptor Ligands. 12: SAR Studies on Hexahydro-dibenz[d,g]azecines Lead to 4-Chloro-7-methyl-5,6,7,8,9,14-hexahydrodibenz[d,g]azecin-3-ol, the First Picomolar D5-Selective Dopamine-Receptor Antagonist-Reference-Cited by-同舟云学术

Dopamine/Serotonin Receptor Ligands. 12: SAR Studies on Hexahydro-dibenz[d,g]azecines Lead to 4-Chloro-7-methyl-5,6,7,8,9,14-hexahydrodibenz[d,g]azecin-3-ol, the First Picomolar D5-Selective Dopamine-Receptor Antagonist

Published:2006-02-17 Issue:6 Volume:49 Page:2110-2116
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Mohr Patrick¹,Decker Michael¹,Enzensperger Christoph¹,Lehmann Jochen¹

Affiliation:

1. Institut für Pharmazie, Lehrstuhl für Pharmazeutische/Medizinische Chemie, Friedrich-Schiller-Universität Jena, Philosophenweg 14, D-07743 Jena, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm051237e

Reference18 articles.

1. Compounds selective for dopamine receptor subtypes

2. Locomotor and discriminative-stimulus effects of cocaine in dopamine D 5 receptor knockout mice

3. Dopamine/serotonin receptor ligands. Part VIII[1]:the dopamine receptor antagonist LE300 - modelled and X-ray structure plus further pharmacological characterization, including serotonin receptor binding, biogenic amine transporter testing and in vivo testings

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