Mechanosynthesis of a Coamorphous Formulation of Creatine with Citric Acid and Humidity-Mediated Transformation into a Cocrystal

Author:

Pekar Kyle B.1,Lefton Jonathan B.1,McConville Christina A.1,Burleson Jewel1,Sethio Daniel1ORCID,Kraka Elfi1,Runčevski Tomče1ORCID

Affiliation:

1. Department of Chemistry, Southern Methodist University, Dallas, Texas 75275, United States

Funder

Welch Foundation

Publisher

American Chemical Society (ACS)

Subject

Condensed Matter Physics,General Materials Science,General Chemistry

Reference64 articles.

1. Creatine and Creatinine Metabolism

2. The Merck Index Online. 2020. Available at https://www.rsc.org/merck-index (Accessed 16 September 2020).

3. Miller, D. W.; Vennerstrom, J. L.; Faulkner, M. C. Creatine oral supplementation using creatine hydrochloride salt. U.S. Patent No. US7,608,641B2, Oct. 27, 2009.

4. Analysis of the efficacy, safety, and regulatory status of novel forms of creatine

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