Development of New Deoxycytidine Kinase Inhibitors and Noninvasive in Vivo Evaluation Using Positron Emission Tomography-Reference-Cited by-同舟云学术

Development of New Deoxycytidine Kinase Inhibitors and Noninvasive in Vivo Evaluation Using Positron Emission Tomography

Published:2013-08-15 Issue:17 Volume:56 Page:6696-6708
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Murphy Jennifer M.,Armijo Amanda L.,Nomme Julian¹,Lee Chi Hang,Smith Quentin A.,Li Zheng,Campbell Dean O.,Liao Hsiang-I,Nathanson David A.,Austin Wayne R.,Lee Jason T.,Darvish Ryan,Wei Liu,Wang Jue,Su Ying¹,Damoiseaux Robert,Sadeghi Saman,Phelps Michael E.,Herschman Harvey R.,Czernin Johannes,Alexandrova Anastassia N.,Jung Michael E.,Lavie Arnon¹,Radu Caius G.

Affiliation:

1. Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, 900 S. Ashland Avenue, M/C 669, Chicago, Illinois 60607, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm400457y

Reference45 articles.

1. INTERACTIONS BETWEEN DEOXYRIBONUCLEOTIDE AND DNA SYNTHESIS

2. Mammalian deoxyribonucleoside kinases

3. Structural Basis for Substrate Promiscuity of dCK

4. Reaction of human UMP-CMP kinase with natural and analog substrates

5. Novel Role of 3-Phosphoglycerate Kinase, a Glycolytic Enzyme, in the Activation of L-Nucleoside Analogs, a New Class of Anticancer and Antiviral Agents

Cited by 24 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Iodine-Mediated Heterocyclization for the Synthesis of 6-Alkylthio-1,3,5-triazine-2,4-diamines from N-Alkylpyridinium Salts and NH₄SCN;The Journal of Organic Chemistry;2023-12-19

2. From a drug repositioning to a structure-based drug design approach to tackle acute lymphoblastic leukemia;Nature Communications;2023-05-29

3. Targeting deoxycytidine kinase improves symptoms in mouse models of multiple sclerosis;Immunology;2022-09-04

4. Development and preclinical pharmacology of a novel dCK inhibitor, DI-87;Biochemical Pharmacology;2020-02

5. The novel L-nucleoside analogue, 5-Fluorotroxacitabine, displays potent efficacy against acute myeloid leukemia;Haematologica;2019-12-19