Mechanism Inspired Development of Rationally Designed Dihydrofolate Reductase Inhibitors as Anticancer Agents
Author:
Affiliation:
1. Department of Chemistry, Guru Nanak Dev University, Amritsar-143005, India
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm300644g
Reference26 articles.
1. Groff, J. P.A Structure–Function Study of Dihydrofolate Reductase: The Role of Tryptophan Residues. Ph.D. Thesis, University of Iowa, 1980.
2. 5-Benzyl-2,4-diaminopyrimidines as Antibacterial Agents. I. Synthesis and Antibacterial Activity in vitro
3. Metabolism of Trimethoprim in Man and Measurement of a New Metabolite: A New Fluorescence Assay
4. Fluorinated Pyrimidines, A New Class of Tumour-Inhibitory Compounds
5. Anticancer activity of 5-fluorouracil available in NCI data base (www.dtp.nci.nih.gov), NSC 19893.
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