Process Intensification via End-to-End Continuous Manufacturing of Atorvastatin Calcium Using an Integrated, Modular Reaction-Crystallization-Spherical Agglomeration-Filtration-Drying Process

Author:

Parvaresh Rojan1ORCID,Nagy Zoltan K.1ORCID

Affiliation:

1. Davidson School of Chemical Engineering, Purdue University, West Lafayette, Indiana 47907, United States

Funder

U.S. Food and Drug Administration

Publisher

American Chemical Society (ACS)

Reference82 articles.

1. Modernizing Pharmaceutical Manufacturing: from Batch to Continuous Production

2. U.S. Food and Drug Administration. Quality Considerations for Continuous Manufacturing; Draft Guidance for Industry. Published 2019. Accessed March 11, 2024. https://www.federalregister.gov/documents/2019/02/27/2019-03413/quality-considerations-for-continuous-manufacturing-draft-guidance-for-industry-availability.

3. Continuous Processing in the Pharmaceutical Industry

4. Economic Analysis of Integrated Continuous and Batch Pharmaceutical Manufacturing: A Case Study

5. Evaluating the potential for the continuous processing of pharmaceutical products—a supply network perspective

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