Process Development and Large-Scale Synthesis of BTK Inhibitor BIIB068-Reference-Cited by-同舟云学术

Process Development and Large-Scale Synthesis of BTK Inhibitor BIIB068

Published:2020-04-22 Issue:6 Volume:24 Page:1199-1206
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Li Chaomin¹^ORCID,Franklin Lloyd¹,Chen Robbie¹,Mack Tamera¹,Humora Michael¹,Ma Bin²,Hopkins Brian T.²,Guzowski John¹,Zheng Fengmei³,MacPhee Michael³,Lin Yiqing³,Ferguson Steven¹,Patience Daniel¹,Moniz George A.⁴,Kiesman William F.¹,O’Brien Erin M.¹

Affiliation:

1. Chemical Process Development, Biogen, 225 Binney Street, Cambridge, Massachusetts 02142, United States

2. Medicinal Chemistry, Biogen, 225 Binney Street, Cambridge, Massachusetts 02142, United States

3. Pharmaceutical Sciences, Biogen, 225 Binney Street, Cambridge, Massachusetts 02142, United States

4. CMC Management, Biogen, 225 Binney Street, Cambridge, Massachusetts 02142, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.0c00087

Reference18 articles.

1. Development of BTK inhibitors for the treatment of B-cell malignancies

2. Targeting Bruton's tyrosine kinase signaling as an emerging therapeutic agent of B-cell malignancies

3. Development of Bruton’s Tyrosine Kinase Inhibitors for Rheumatoid Arthritis

4. The development of Bruton's tyrosine kinase (BTK) inhibitors from 2012 to 2017: A mini-review

5. The Eight Criteria Defining a Good Chemical Manufacturing Process

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