Intensification of Continuous Ortho-Lithiation at Ambient Conditions—Process Understanding and Assessment of Sustainability Benefits-Reference-Cited by-同舟云学术

Intensification of Continuous Ortho-Lithiation at Ambient Conditions—Process Understanding and Assessment of Sustainability Benefits

Published:2017-07-24 Issue:9 Volume:21 Page:1259-1271
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Feng Ruili¹²,Ramchandani Sushil²,Ramalingam Balamurugan³,Tan Song Wei Benjamin²,Li Chuanzhao¹,Teoh Soo Khean²,Boodhoo Kamelia¹,Sharratt Paul²

Affiliation:

1. School of Chemical Engineering and Advanced Materials, Newcastle University, Newcastle Upon Tyne, NE1 7RU, United Kingdom

2. INCOME Team, Process Science and Modelling Group, Institute of Chemical and Engineering Sciences (ICES), 1 Pesek Road, Jurong Island, Singapore 627833

3. Organic Chemistry Group, Institute of Chemical and Engineering Sciences (ICES), Neuros 8 Biomedical Grove Neuros Building, Singapore 138665

Funder

Economic Development Board - Singapore

GlaxoSmithKline

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.7b00142

Reference30 articles.

1. Directed ortho metalation of n,n-diethyl benzamides. Methodology and regiospecific synthesis of useful contiguously tri- and tetra-substituted oxygenated aromatics, phthalides and phthalic anhydrides

2. Manufacturing Synthesis of 5-Substituted Phthalides

3. Phthalides and Phthalans: Synthetic Methodologies and Their Applications in the Total Synthesis

4. Experience with Scale-Up of Low-Temperature Organometallic Reactions in Continuous Flow

5. Microreactor Technology and Continuous Processes in the Fine Chemical and Pharmaceutical Industry: Is the Revolution Underway?

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