Synthesis of the C1–C13 Fragment of Eribulin on a Kilogram Scale
Author:
Affiliation:
1. R&D Center, Yonsung Fine Chemicals Company Limited, Innoplex-2-dong, 306, Sinwon-ro, Yeongtong-gu, Suwon-si 16675, Gyeonggi-do, Republic of Korea
Funder
Ministry of Trade, Industry and Energy
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.1c00295
Reference21 articles.
1. Eribulin monotherapy versus treatment of physician's choice in patients with metastatic breast cancer (EMBRACE): a phase 3 open-label randomised study
2. Eribulin mesylate: A novel halichondrin B analogue for the treatment of metastatic breast cancer
3. Systematic review of Real-World effectiveness of eribulin for locally advanced or metastatic breast cancer
4. FDA Approval Summary: Eribulin for Patients with Unresectable or Metastatic Liposarcoma Who Have Received a Prior Anthracycline-Containing Regimen
5. Perspectives on the mechanism of action and clinical application of eribulin for metastatic breast cancer
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1. Proprietary Synthesis of the C27–C35 Fragment of Eribulin and Its Elaboration toward the C14–C35 Subunit;Organic Process Research & Development;2024-06-28
2. Comprehensive review on the elaboration of payloads derived from natural products for antibody-drug conjugates;European Journal of Medicinal Chemistry;2024-03
3. Scalable synthesis of the C14–C23 fragment of Eribulin and Halichondrin B;Bulletin of the Korean Chemical Society;2022-09-27
4. Synthesis of the C1–C13 Fragment of Eribulin;Synfacts;2022-03-18
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