Identification of an Unexpected Impurity in a New Improved Synthesis of Lesinurad-Reference-Cited by-同舟云学术

Identification of an Unexpected Impurity in a New Improved Synthesis of Lesinurad

Published:2018-11-29 Issue:12 Volume:22 Page:1861-1867
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Halama Aleš¹^ORCID,Stach Jan¹,Rádl Stanislav¹,Benediktová Kristýna¹

Affiliation:

1. Department of Chemical Synthesis, Zentiva k.s., U kabelovny 130, Prague 102 01, Czech Republic

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.8b00316

Reference22 articles.

1. Lesinurad: First Global Approval

2. Renal Transport of Uric Acid: Evolving Concepts and Uncertainties

3. Lesinurad/Allopurinol (Duzallo) for Gout-Associated Hyperuricemia

4. a Quart, B. D.; Girardet, J. L.; Gunic, E.; Yeh, L. T. Preparation of azole carboxylates as modulators of blood uric acid levels. WO2009070740 A2, 2009.

5. The development of an effective synthetic route of lesinurad (RDEA594)

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