Expeditious Synthesis of a Potent Allosteric HIV-1 Integrase Inhibitor GSK3839919A-Reference-Cited by-同舟云学术

Expeditious Synthesis of a Potent Allosteric HIV-1 Integrase Inhibitor GSK3839919A

Published:2023-01-09 Issue:1 Volume:27 Page:217-226
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Bobko Mark A.¹,Elward Jennifer M.²,Naidu B. Narasimhulu³^ORCID,Nieves-Quinones Yexenia E.¹,Reiher Christopher A.¹,Su Qiaogong¹^ORCID,Sun Liang⁴,Woodard John¹,Xie Shiping¹^ORCID,Yang Wuxing⁴,Yin Yunxing⁴

Affiliation:

1. Drug Substance Development, GSK, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States

2. Molecular Design, GSK, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States

3. ViiV Healthcare, Branford, Connecticut 06405, United States

4. Chemistry Service Unit, WuXi AppTec Co., Ltd., 168 Nanhai Road, Tianjin 300457, People’s Republic of China

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.2c00343

Reference27 articles.

1. Recent advances in the discovery of small-molecule inhibitors of HIV-1 integrase

2. Discovery of Raltegravir, a Potent, Selective Orally Bioavailable HIV-Integrase Inhibitor for the Treatment of HIV-AIDS Infection

3. A Review of the Efficacy and Safety of Genvoya® (Elvitegravir, Cobicistat, Emtricitabine, and Tenofovir Alafenamide) in the Management of HIV-1 Infection

4. Carbamoyl Pyridone HIV-1 Integrase Inhibitors 3. A Diastereomeric Approach to Chiral Nonracemic Tricyclic Ring Systems and the Discovery of Dolutegravir (S/GSK1349572) and (S/GSK1265744)

5. Bictegravir: First Global Approval

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Synthetic Advantages of Defluorinative C−F Bond Functionalization;Angewandte Chemie;2023-09-14

2. Synthetic Advantages of Defluorinative C−F Bond Functionalization;Angewandte Chemie International Edition;2023-09-14