Chemoenzymatic Sequential Multistep One-Pot Reaction for the Synthesis of (1S,2R)-1-(Methoxycarbonyl)cyclohex-4-ene-2-carboxylic Acid with Recombinant Pig Liver Esterase

Author:

Süss Philipp12,Borchert Sonja1,Hinze Janine3,Illner Sabine3,von Langermann Jan3,Kragl Udo3,Bornscheuer Uwe T.2,Wardenga Rainer1

Affiliation:

1. Enzymicals AG, Walther-Rathenau-Str. 49a, 17489 Greifswald, Germany

2. Institute of Biochemistry, University of Greifswald, Felix-Hausdorff-Str. 4, 17487 Greifswald, Germany

3. Institute of Chemistry, University of Rostock, Albert-Einstein-Str. 3a, 18059 Rostock, Germany

Funder

Bundesministerium fur Wirtschaft und Technologie

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Reference24 articles.

1. Federsel, H.J.InChirality in Drug Research;Francotte, E., Lindner, W., Mannhold, R., Kubinyi, H., Folkers, G., Eds.Wiley-VCH:Weinheim, 2006; pp27–65.

2. Engineering the third wave of biocatalysis

3. Kazlauskas, R. J.; Kim, B.G.InBiocatalysis for Green Chemistry and Chemical Process Development;Tao, J.; Kazlauskas, R. J., Eds.John Wiley & Sons, Inc.:Hoboken, NJ, 2011; pp1–22.

4. Cossy, J. R.InComprehensive Chirality,Carreira, E. M.; Yamamoto, H., Eds.Elsevier:Amsterdam, 2012; pp1–7.

5. Bornscheuer, U. T.; Kazlauskas, R. J.Hydrolases in Organic Synthesis;Wiley-VCH:Weinheim, 2006; pp141–183.

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