Handling Hazards Using Continuous Flow Chemistry: Synthesis of N1-Aryl-[1,2,3]-triazoles from Anilines via Telescoped Three-Step Diazotization, Azidodediazotization, and [3 + 2] Dipolar Cycloaddition Processes-Reference-Cited by-同舟云学术

Handling Hazards Using Continuous Flow Chemistry: Synthesis of N1-Aryl-[1,2,3]-triazoles from Anilines via Telescoped Three-Step Diazotization, Azidodediazotization, and [3 + 2] Dipolar Cycloaddition Processes

Published:2016-10-17 Issue:11 Volume:20 Page:1967-1973
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Teci Matthieu¹,Tilley Michael¹,McGuire Michael A.²,Organ Michael G.¹³

Affiliation:

1. Department of Chemistry, York University, 4700 Keele Street, Toronto, Ontario M3J1P3, Canada

2. GlaxoSmithKline Pharmaceuticals Inc., 709 Swedeland Road, P.O. Box 1539, UMW 2810, King of Prussia, Pennsylvania 19406, United States

3. Centre for Catalysis Research and Innovation (CCRI) and Department of Chemistry, University of Ottawa, Ottawa, Ontario K1N6N5, Canada

Funder

Natural Sciences and Engineering Research Council of Canada

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.6b00292

Reference105 articles.

1. Scaling Out by Microwave-Assisted, Continuous Flow Organic Synthesis (MACOS): Multi-Gram Synthesis of Bromo- and Fluoro-benzofused Sultams Benzthiaoxazepine-1,1-dioxides

2. The Microwave-to-Flow Paradigm: Translating High-Temperature Batch Microwave Chemistry to Scalable Continuous-Flow Processes

3. Novel process windows – Concept, proposition and evaluation methodology, and intensified superheated processing

4. Novel Process Windows for Enabling, Accelerating, and Uplifting Flow Chemistry

5. Continuous-Flow Technology-A Tool for the Safe Manufacturing of Active Pharmaceutical Ingredients

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