Development of a Scalable and Sustainable High Performance CounterCurrent Chromatography (HPCCC) Purification for Spinosyn A and Spinosyn D from Spinosad

Author:

DeAmicis Carl1,Yang Qiang1ORCID,Bright Colin2,Edwards Neil A.2,Harris Guy H.2,Kaur Sandeep2,Wood Philip L.2,Hewitson Peter3,Ignatova Svetlana3

Affiliation:

1. Process Chemistry, Dow AgroSciences, 9330 Zionsville Rd., Indianapolis, Indiana 46268, United States

2. Dynamic Extractions, Ltd., Unit 30, Tafarnaubach Industrial Estate, Tredegar, Blaenau Gwent, Wales NP22 3AA, U.K.

3. Advanced Bioprocessing Centre, Brunel University London, Uxbridge, Middlesex, UB8 3PH, U.K.

Funder

Dow AgroSciences

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Reference23 articles.

1. Dripps, J. E.; Boucher, R. E.; Chloridis, A.; Cleveland, C. B.; DeAmicis, C. V.; Gomez, L. E.; Paroonagian, D. L.; Pavan, L. A.; Sparks, T. C.; Watson, G. B.Green Trends in Insect Control, RSC Green Chemistry No. 11;The Royal Society of Chemistry:London, 2011; p163.

2. Spinosad Toxicity to Pollinators and Associated Risk

3. A Reduced Risk Insecticide for Organic Agriculture: Spinosad Case Study

4. https://www.epa.gov/greenchemistry/presidential-green-chemistry-challenge-1999-designing-greener-chemicals-award(accessed July 18, 2017) .

5. Total synthesis of (+)-A83543A [(+)-lepicidin A]

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