Investigation of Reaction Mechanisms of Drug Degradation in the Solid State: A Kinetic Study Implementing Ultrahigh-Performance Liquid Chromatography and High-Resolution Mass Spectrometry for Thermally Stressed Thyroxine-Reference-Cited by-同舟云学术

Investigation of Reaction Mechanisms of Drug Degradation in the Solid State: A Kinetic Study Implementing Ultrahigh-Performance Liquid Chromatography and High-Resolution Mass Spectrometry for Thermally Stressed Thyroxine

Published:2013-01-30 Issue:4 Volume:85 Page:2385-2390
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Neu Volker¹,Bielow Chris²,Schneider Peter³,Reinert Knut²,Stuppner Hermann³,Huber Christian G.¹

Affiliation:

1. Department of Molecular Biology, Division of Chemistry and Bioanalytics, University of Salzburg, Hellbrunner Strasse 34, 5020 Salzburg, Austria

2. Department for Computer Science and Mathematics, Algorithmic Bioinformatics, Free University of Berlin, Takustrasse 9, 14195 Berlin, Germany

3. Institute of Pharmacy, Pharmacognosy, Member of CMBI, University of Innsbruck, Innrain 80-82, 6020 Innsbruck, Austria

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ac303404e

Reference24 articles.

1. Committee for Medicinal Products for Human Use. Guideline on Safety and Efficacy Follow-Up Risk Management of Advanced Therapy Medicinal Products;European Medicines Agency:London, 2008.

2. The Mechanism of Action of Thyroid Hormones

3. Thyroid hormone testing by tandem mass spectrometry

4. Treatment of Hypothyroidism with Combinations of Levothyroxine plus Liothyronine

5. ISOLATION OF THE IODINE COMPOUND WHICH OCCURS IN THE THYROID

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