Enzymatic Cβ–H Functionalization of l-Arg and l-Leu in Nonribosomally Derived Peptidyl Natural Products: A Tale of Two Oxidoreductases-Reference-Cited by-同舟云学术

Enzymatic Cβ–H Functionalization of l-Arg and l-Leu in Nonribosomally Derived Peptidyl Natural Products: A Tale of Two Oxidoreductases

Published:2021-11-12 Issue:46 Volume:143 Page:19425-19437
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Cui Zheng¹,Nguyen Han¹,Bhardwaj Minakshi¹,Wang Xiachang¹^ORCID,Büschleb Martin²,Lemke Anke³,Schütz Christian³,Rohrbacher Christian³,Junghanns Pierre³,Koppermann Stefan³,Ducho Christian³^ORCID,Thorson Jon S.¹^ORCID,Van Lanen Steven G.¹^ORCID

Affiliation:

1. Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky 40536, United States

2. Department of Chemistry, Institute of Organic and Biomolecular Chemistry, Georg-August-University, GöTammannstr. 2, 37077 Göttingen, Germany

3. Department of Pharmacy, Pharmaceutical and Medicinal Chemistry, Saarland University, Campus C2 3, 66123 Saarbrücken, Germany

Funder

National Institute of Allergy and Infectious Diseases

Deutsche Forschungsgemeinschaft

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.1c08177

Reference71 articles.

1. Late‐Stage Peptide Diversification through Cobalt‐Catalyzed C−H Activation: Sequential Multicatalysis for Stapled Peptides

2. Oxidative diversification of amino acids and peptides by small-molecule iron catalysis

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4. Carter, G. T.; Lotvin, J. A.; McDonald, L. A. U.S. Patent 20030104986A1, June 5, 2003.

5. Structures of the Muraymycins, Novel Peptidoglycan Biosynthesis Inhibitors

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