Novel Benzo[b]thiophene Derivatives as New Potential Antidepressants with Rapid Onset of Action-Reference-Cited by-同舟云学术

Novel Benzo[b]thiophene Derivatives as New Potential Antidepressants with Rapid Onset of Action

Published:2011-04-06 Issue:8 Volume:54 Page:3086-3090
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Berrade Luis¹²,Aisa Bárbara³,Ramirez María J.³,Galiano Silvia¹,Guccione Salvatore²,Moltzau Lise Román⁴,Levy Finn Olav⁴,Nicoletti Ferdinando⁵⁶,Battaglia Giuseppe⁶,Molinaro Gemma⁶,Aldana Ignacio¹,Monge Antonio¹,Perez-Silanes Silvia¹

Affiliation:

1. Unidad en Investigación y Desarrollo de Medicamentos, Centro de Investigación en Farmacobiología Aplicada (CIFA), University of Navarra, C/Irunlarrea 1, 31080 Pamplona, Spain

2. Dipartimento di Scienze del Farmaco, University of Catania, V. le Andrea Doria 6 Ed, 2 Città Universitaria, I-95125, Catania, Italy

3. Department of Pharmacology, University of Navarra, C/Irunlarrea 1, 31080 Pamplona, Spain

4. Department of Pharmacology, University of Oslo and Oslo University Hospital, N-0316 Oslo, Norway

5. I.R.C.C.S. Instituto Neurologico Mediterraneo Neuromed, Localitá Camerelle, 86077 Pozzilli (IS), Italy

6. Department of Physiology and Pharmacology, University of Rome Sapienza, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm2000773

Reference28 articles.

1. New 3-[4-(aryl)piperazin-1-yl]-1-(benzo[b]thiophen-3-yl)propane derivatives with dual action at 5-HT1A serotonin receptors and serotonin transporter as a new class of antidepressants

2. New 1-Aryl-3-(4-arylpiperazin-1-yl)propane Derivatives, with Dual Action at 5-HT1A Serotonin Receptors and Serotonin Transporter, as a New Class of Antidepressants

3. Synthesis and Molecular Modeling of New 1-Aryl-3-[4-arylpiperazin-1-yl]-1-propane Derivatives with High Affinity at the Serotonin Transporter and at 5-HT1A Receptors

4. The 5-HT7 receptor and disorders of the nervous system: an overview

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