Purifying the Masses: Integrating Prepurification Quality Control, High-Throughput LC/MS Purification, and Compound Plating To Feed High-Throughput Screening-Reference-Cited by-同舟云学术

Purifying the Masses: Integrating Prepurification Quality Control, High-Throughput LC/MS Purification, and Compound Plating To Feed High-Throughput Screening

Published:2005-02-04 Issue:2 Volume:7 Page:210-217
ISSN:1520-4766
Container-title:Journal of Combinatorial Chemistry
language:en
Short-container-title:J. Comb. Chem.

Author:

Isbell John J.¹,Zhou Yingyao¹,Guintu Christina¹,Rynd Matthew¹,Jiang Shumei¹,Petrov Dimitri¹,Micklash Ken¹,Mainquist Jim¹,Ek Jared¹,Chang Jim¹,Weselak Mark¹,Backes Bradley J.¹,Brailsford Andrew¹,Shave Darcy¹

Affiliation:

1. Genomics Institute of the Novartis Research Foundation (GNF), 10675 John Jay Hopkins Drive, San Diego, California 92121, Metabolic Disease Research, Abbott Laboratories, 100 Abbott Park Road, Abbott Park, Illinois 60064-6099, and Waters Corporation, 34 Maple Street, Milford, Massachusetts 01757-3696

Publisher

American Chemical Society (ACS)

Subject

General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/cc049892f

Reference40 articles.

1. Reactive compounds and in vitro false positives in HTS

2. Nonleadlikeness and leadlikeness in biochemical screening

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