The Sigma Enigma: In Vitro/in Silico Site-Directed Mutagenesis Studies Unveil σ1 Receptor Ligand Binding-Reference-Cited by-同舟云学术

The Sigma Enigma: In Vitro/in Silico Site-Directed Mutagenesis Studies Unveil σ1 Receptor Ligand Binding

Published:2014-04-28 Issue:18 Volume:53 Page:2993-3003
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Brune S.¹,Schepmann D.¹,Klempnauer K.-H.²,Marson D.³,Dal Col V.³,Laurini E.³,Fermeglia M.³,Wünsch B.¹,Pricl S.³⁴

Affiliation:

1. Institut für Pharmazeutische und Medizinische Chemie, Westfälische Wilhelms-Universität Münster, Corrensstraße 48, D-48149 Münster, Germany

2. Institut für Biochemie, Westfälischen Wilhelms-Universität Münster, Wilhelm-Klemm-Straße 2, D-48149 Münster, Germany

3. Molecular Simulation Engineering (MOSE) Laboratory, Department of Engineering and Architecture (DEA), University of Trieste, Via Valerio 10, 34127 Trieste, Italy

4. National Interuniversity Consortium for Material Science and Technology (INSTM), Research Unit MOSE-DEA, University of Trieste, Trieste, Italy

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi401575g

Reference42 articles.

1. σ Receptors: potential medications development target for anti-cocaine agents

2. Phencyclidine and σ opiate receptors in brain: Biochemical and autoradiographical differentiation

3. ??-1 Receptor Ligands

4. The Hallucinogen N,N -Dimethyltryptamine (DMT) Is an Endogenous Sigma-1 Receptor Regulator

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