Flexible 3D Cell-Based Platforms for the Discovery and Profiling of Novel Drugs Targeting Plasmodium Hepatic Infection-Reference-Cited by-同舟云学术

Flexible 3D Cell-Based Platforms for the Discovery and Profiling of Novel Drugs Targeting Plasmodium Hepatic Infection

Published:2019-09-03 Issue:11 Volume:5 Page:1831-1842
ISSN:2373-8227
Container-title:ACS Infectious Diseases
language:en
Short-container-title:ACS Infect. Dis.

Author:

Arez Francisca¹²,Rebelo Sofia P.¹²,Fontinha Diana³,Simão Daniel¹²,Martins Tatiana R.¹²,Machado Marta³,Fischli Christoph⁴⁵,Oeuvray Claude⁶,Badolo Lassina⁷,Carrondo Manuel J. T.¹²,Rottmann Matthias⁴⁵,Spangenberg Thomas⁶^ORCID,Brito Catarina¹²,Greco Beatrice⁶,Prudêncio Miguel³,Alves Paula M.¹²^ORCID

Affiliation:

1. iBET, Instituto de Biologia Experimental e Tecnológica, Apartado 12, 2780-901 Oeiras, Portugal

2. Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Avenida da República, 2780-157 Oeiras, Portugal

3. Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, 1649-028 Lisboa, Portugal

4. Swiss Tropical and Public Health Institute, Basel 4051, Switzerland

5. University of Basel, Basel 4003, Switzerland

6. Global Health Institute of Merck, Ares Trading S.A., a subsidiary of Merck KGaA, Darmstadt, Germany, 1262 Eysins, Switzerland

7. Discovery and Development Technologies, Merck Healthcare KGaA, Frankfurter Strasse 250, 64293 Darmstadt, Germany

Funder

Merck KGaA

Funda??o para a Ci?ncia e a Tecnologia

Publisher

American Chemical Society (ACS)

Subject

Infectious Diseases

Link

https://pubs.acs.org/doi/pdf/10.1021/acsinfecdis.9b00144

Reference45 articles.

1. (2018) World malaria report 2018, World Health Organization.

2. Migration through host cells activates Plasmodium sporozoites for infection

3. The silent path to thousands of merozoites: the Plasmodium liver stage

4. Targeting the hypnozoite reservoir of Plasmodium vivax: the hidden obstacle to malaria elimination

5. Current therapies and future possibilities for drug development against liver-stage malaria

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