Nanoparticle Formulation of Moxifloxacin and Intramuscular Route of Delivery Improve Antibiotic Pharmacokinetics and Treatment of Pneumonic Tularemia in a Mouse Model

Author:

Clemens Daniel L.1ORCID,Lee Bai-Yu1,Plamthottam Sheba2,Tullius Michael V.1,Wang Ruining2,Yu Chia-Jung2,Li Zilu2,Dillon Barbara Jane1,Zink Jeffrey I.23ORCID,Horwitz Marcus A.1

Affiliation:

1. Division of Infectious Diseases, Department of Medicine, University of California, CHS 37-121, 10833 Le Conte Avenue, Los Angeles, California 90095-1688, United States

2. Department of Chemistry and Biochemistry, University of California, 3013 Young Drive East, Los Angeles, California 90095-1569, United States

3. California NanoSystems Institute, University of California, Los Angeles, California 90095-8352, United States

Funder

Defense Threat Reduction Agency

Publisher

American Chemical Society (ACS)

Subject

Infectious Diseases

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