Synthesis and Biological Activity of Various Derivatives of a Novel Class of Potent, Selective, and Orally Active Prostaglandin D2 Receptor Antagonists. 2. 6,6-Dimethylbicyclo[3.1.1]heptane Derivatives
Author:
Affiliation:
1. Shionogi Research Laboratories, Shionogi & Co., Ltd., 12-4, Sagisu 5-chome, Fukushima-ku, Osaka 553-0002, Japan
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm0205189
Reference60 articles.
1. Bicyclo[2.2.1]heptane and 6,6-Dimethylbicyclo[3.1.1]heptane Derivatives: Orally Active, Potent, and Selective Prostaglandin D2 Receptor Antagonists
2. Prostaglandin D2-induced bronchoconstriction is mediated only in part by the thromboxane prostanoid receptor
3. Antigen-Induced Bronchial Anaphylaxis in Actively Sensitized Guinea Pigs. The Effect of Booster Injection and Cyclophosphamide Treatment
4. Prostaglandin D 2 as a Mediator of Allergic Asthma
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