Discovery of Aryl Aminoquinazoline Pyridones as Potent, Selective, and Orally Efficacious Inhibitors of Receptor Tyrosine Kinase c-Kit-Reference-Cited by-同舟云学术

Discovery of Aryl Aminoquinazoline Pyridones as Potent, Selective, and Orally Efficacious Inhibitors of Receptor Tyrosine Kinase c-Kit

Published:2008-05-01 Issue:11 Volume:51 Page:3065-3068
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hu Essa¹,Tasker Andrew¹,White Ryan D.¹,Kunz Roxanne K.¹,Human Jason¹,Chen Ning¹,Bürli Roland¹,Hungate Randall¹,Novak Perry¹,Itano Andrea¹,Zhang Xuxia¹,Yu Violeta¹,Nguyen Yen¹,Tudor Yanyan¹,Plant Matthew¹,Flynn Shaun¹,Xu Yang¹,Meagher Kristin L.¹,Whittington Douglas A.¹,Ng Gordon Y.¹

Affiliation:

1. Department of Medicinal Chemistry, Department of Inflammation, Department of HTS and Molecular Pharmacology, Department of Pharmacokinetics and Drug Metabolism, Department of Molecular Structures, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320-1799 Department of Medicinal Chemistry, Department of Small Molecule Process Development, Amgen Inc., One Kendall Square, Building 1000, Cambridge, Massachusetts 02139

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm800188g

Reference43 articles.

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