Discovery and Development of α7 Nicotinic Acetylcholine Receptor Modulators
Author:
Affiliation:
1. Targacept, Inc., 200 E. First Street, Winston-Salem, North Carolina 27101-4165, United States
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm2007672
Reference108 articles.
1. Nicotinic agonists competitively antagonize serotonin at mouse 5-HT3 receptors expressed in Xenopus oocytes
2. Toward a structural basis for the function of nicotinic acetylcholine receptors and their cousins
3. High affinity ligands for the α7 nicotinic receptor that show no cross-reactivity with the 5-HT3 receptor
4. The 5-HT 3 antagonist tropisetron (ICS 205-930) is a potent and selective α7 nicotinic receptor partial agonist
5. 5-HT3 Receptors
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