Synthesis and Antiviral Activity of (Z)- and (E)-2,2-[Bis(hydroxymethyl)cyclopropylidene]methylpurines and -pyrimidines: Second-Generation Methylenecyclopropane Analogues of Nucleosides-Reference-Cited by-同舟云学术

Synthesis and Antiviral Activity of (Z)- and (E)-2,2-[Bis(hydroxymethyl)cyclopropylidene]methylpurines and -pyrimidines: Second-Generation Methylenecyclopropane Analogues of Nucleosides

Published:2003-12-23 Issue:3 Volume:47 Page:566-575
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zhou Shaoman¹,Breitenbach Julie M.¹,Borysko Katherine Z.¹,Drach John C.¹,Kern Earl R.¹,Gullen Elizabeth¹,Cheng Yung-Chi¹,Zemlicka Jiri¹

Affiliation:

1. Department of Chemistry, Developmental Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, Michigan 48201-1379, Department of Biologic and Materials Science, School of Dentistry, University of Michigan, Ann Arbor, Michigan 48019-1078, Department of Pediatrics, The University of Alabama School of Medicine, Birmingham, Alabama 35233, and Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut 06510-8066

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm030316s

Reference28 articles.

1. Effective treatment of murine cytomegalovirus infections with methylenecyclopropane analogues of nucleosides

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