Cofactor Activation and Substrate Binding in Pyruvate Decarboxylase. Insights into the Reaction Mechanism from Molecular Dynamics Simulations
Author:
Affiliation:
1. Danish National Research Foundation, Center for Catalysis, and the Department of Chemistry, Aarhus University, DK-8000 Aarhus C, Denmark
Publisher
American Chemical Society (ACS)
Subject
Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/bi051134y
Reference87 articles.
1. Thiamin diphosphate: a mechanistic update on enzymic and nonenzymic catalysis of decarboxylation
2. Mechanism of Thiamine-catalyzed Reactions1
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