Optimization of (Arylpiperazinylbutyl)oxindoles Exhibiting Selective 5-HT7 Receptor Antagonist Activity-Reference-Cited by-同舟云学术

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Optimization of (Arylpiperazinylbutyl)oxindoles Exhibiting Selective 5-HT7 Receptor Antagonist Activity

Published:2011-09-16 Issue:19 Volume:54 Page:6657-6669
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Volk Balázs¹,Gacsályi István²,Pallagi Katalin²,Poszávácz László¹,Gyönös Ildikó²,Szabó Éva²,Bakó Tibor¹,Spedding Michael³,Simig Gyula¹,Szénási Gábor²

Affiliation:

1. Chemical Research Division, EGIS Pharmaceuticals Plc., P.O. Box 100, Budapest, H-1475 Hungary

2. Preclinical Research Division, EGIS Pharmaceuticals Plc., P.O. Box 100, Budapest, H-1475 Hungary

3. Les Laboratoires Servier, 22 rue Garnier, 92578 Neuilly-sur-Seine, France

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm200547z

Reference76 articles.

1. Molecular, pharmacological and functional diversity of 5-HT receptors

2. Higher-End Serotonin Receptors: 5-HT5, 5-HT6, and 5-HT7

3. Impact of adrenalectomy on 5-HT6 and 5-HT7 receptor gene expression in the rat hippocampus

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5. Synthesis and evaluation of 99mTc-labeled 1-(2-Pyridyl)piperazine derivatives as radioligands for 5HT7 receptors;Bioorganic Chemistry;2023-06

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