Novel [99mTcIII(PS)2(Ln)] Mixed-Ligand Compounds (PS = Phosphino-thiolate; L = Dithiocarbamate) Useful in Design and Development of TcIII-Based Agents: Synthesis, in Vitro, and ex Vivo Biodistribution Studies

Author:

Salvarese Nicola1,Morellato Nicolò2,Rosato Antonio13,Meléndez-Alafort Laura1,Refosco Fiorenzo4,Bolzati Cristina4

Affiliation:

1. Dipartimento di Scienze Chirurgiche, Oncologiche e Gastroenterologiche, Università degli Studi di Padova, via Gattamelata 64, 35138 Padua, Italy

2. Dipartimento di Scienze del Farmaco, Università degli Studi di Padova, Via Marzolo 5, 35131 Padua, Italy

3. Istituto Oncologico Veneto, via Gattamelata 64, 35138 Padua, Italy

4. IENI-CNR, Corso Stati Uniti 4, 35127 Padua, Italy

Funder

Associazione Italiana per la Ricerca sul Cancro

Ministero dell'Istruzione, dell'Università e della Ricerca

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Reference42 articles.

1. Is PET always an advantage versus planar and SPECT imaging?

2. Why are investors not interested in my radiotracer? The industrial and regulatory constraints in the development of radiopharmaceuticals

3. The Supply of Medical Radioisotopes; Implementation of the HLG-MR Policy Approach: Results from a Self-assessment by the Global 99Mo/99mTc Supply Chain;Nuclear Development, NEA/SEN/HLGMR(2013)4;OECD, Nuclear Energy Agency, 2013; http://www.oecd-nea.org/ndd/reports/2013/implementation_hlg-mr_policy.pdf(accessed March 2013).

4. The Supply of Medical Radioisotopes; Review of Potential Molybdenum-99/Technetium-99m Production Technologies;Organization for Economic Cooperation and Development/Nuclear Energy Agency Secretariat, 2010; http://www.oecd-nea.org/med-radio/reports/Med-Radio-99Mo-Prod-Tech.pdf(accessed November 2010) .

5. REPORT on the 1st Research Coordination Meeting on "Accelerator-Based Alternatives to Non-HEU Production of 99Mo/99mTc";1st Research Coordination Meeting on "Accelerator-Based Alternatives to Non-HEU Production of99Mo/99mTcVancouver, Canada,April 16-20, 2012;IAEA:Geneva, 2012

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