Total Synthesis of Lehualide B by Allylic Alcohol−Alkyne Reductive Cross-Coupling

Author:

Jeso Valer1,Micalizio Glenn C.1

Affiliation:

1. Department of Chemistry, The Scripps Research Institute, Scripps Florida, Jupiter, Florida 33458

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Reference16 articles.

1. Lehualides A−D, Metabolites from a Hawaiian Sponge of the Genus Plakortis

2. For a recent total synthesis of piericidin B1 and discussion of structure−activity relationships, see:

3. Total Synthesis of Piericidin A1 and B1 and Key Analogues

4. Synthesis of Substituted 1,4-Dienes by Direct Alkylation of Allylic Alcohols

5. For an example of the use of allylic alcohol−alkyne coupling in a recent total synthesis, see:

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