Structure-Based Design and Synthesis of 1,3-Oxazinan-2-one Inhibitors of 11β-Hydroxysteroid Dehydrogenase Type 1-Reference-Cited by-同舟云学术

Structure-Based Design and Synthesis of 1,3-Oxazinan-2-one Inhibitors of 11β-Hydroxysteroid Dehydrogenase Type 1

Published:2011-08-04 Issue:17 Volume:54 Page:6050-6062
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Xu Zhenrong¹,Tice Colin M.¹,Zhao Wei¹,Cacatian Salvacion¹,Ye Yuan-Jie¹,Singh Suresh B.¹,Lindblom Peter¹,McKeever Brian M.¹,Krosky Paula M.¹,Kruk Barbara A.¹,Berbaum Jennifer¹,Harrison Richard K.¹,Johnson Judith A.¹,Bukhtiyarov Yuri¹,Panemangalore Reshma¹,Scott Boyd B.¹,Zhao Yi¹,Bruno Joseph G.¹,Togias Jennifer¹,Guo Joan¹,Guo Rong¹,Carroll Patrick J.²,McGeehan Gerard M.¹,Zhuang Linghang¹,He Wei¹,Claremon David A.¹

Affiliation:

1. Vitae Pharmaceuticals, 502 West Office Center Drive, Fort Washington, Pennsylvania 19034, United States

2. Department of Chemistry, University of Pennsylvania, 250 South 33rd Street, Philadelphia, Pennsylvania 19104, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm2005354

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