Conformational Pseudopolymorphism and Solid-State CPMAS NMR Studies for Determination of Solvent-Dependent Solution-State Conformational Preferences for (−)-Scopolamine Hydrobromide/Hydrochloride Salts
Author:
Affiliation:
1. Department of Chemistry, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel
2. Département de Chimie, Université de Sherbrooke, Québec, Canada J1K 2R1
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/jo9912956
Reference36 articles.
1. The Merck Index, 12th ed.; Budavari, S., Ed.; Merck: Rahway, NJ, 1996; p 1444 and references therein.
2. 632. The stereochemistry of the tropane alkaloids. Part XIV. The absolute configuration of (–)-tropic acid, hyoscyamine, and hyoscine
3. Stereochemistry of the N-methyl group in salts of tropane alkaloids
4. Spectral reassignment and structure elucidation of scopolamine free base through two-dimensional NMR techniques
5. NMR and molecular mechanics studies on the solution-state conformation of (−)-scopolamine free base
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