1. Affiliated Hospital of Nantong University, Nantong 226001, PR China, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, PR China, Changhai Hospital, Secondary Military Medical University, Shanghai 200433, PR China, Shanghai 9th People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, PR China, and Xiamen University, Xiamen 361005, PR China