Development of 2‘-O-Methoxyethyl Phosphorothioate Oligonucleotides as Antisense Drugs under Stereochemical Control
Author:
Affiliation:
1. Isis Pharmaceuticals, Inc., 2282 Faraday Avenue, Carlsbad, California 92008, U.S.A.
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/op020061c
Reference54 articles.
1. Crooke, S. T.Antisense Therapeutics in Biotechnology & GeneticEngineering Reviews; Intercept Ltd: Hampshire, UK, 1998; Vol. 15, pp 121−157.
2. An Overview of Progress in Antisense Therapeutics
3. Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinase
Cited by 10 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Establishing stereochemical comparability in phosphorothioate oligonucleotides with nuclease P1 digestion coupled with LCMS analysis;The Analyst;2023
2. Inhomogeneous Diastereomeric Composition of Mongersen Antisense Phosphorothioate Oligonucleotide Preparations and Related Pharmacological Activity Impairment;Nucleic Acid Therapeutics;2022-08-01
3. Individualized Antisense Oligonucleotide Therapies: How to Approach the Challenge of Manufacturing These Oligos from a Chemistry, Manufacturing, and Control-Regulatory Standpoint;Nucleic Acid Therapeutics;2021-12-28
4. Development of Kilogram-Scale Convergent Liquid-Phase Synthesis of Oligonucleotides;The Journal of Organic Chemistry;2021-11-22
5. Investigating the Activation Kinetics of Phosphoramidites for Oligonucleotide Synthesis;Organic Process Research & Development;2021-10-08
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3