An Integrated Chemo-enzymatic Route for Preparation of β-Thymidine, a Key Intermediate in the Preparation of Antiretrovirals-Reference-Cited by-同舟云学术

An Integrated Chemo-enzymatic Route for Preparation of β-Thymidine, a Key Intermediate in the Preparation of Antiretrovirals

Published:2010-11-02 Issue:1 Volume:15 Page:258-265
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Gordon Gregory E. R.¹,Bode Moira L.¹,Visser Daniel F.¹,Lepuru M. Jerry¹,Zeevaart Jacob G.¹,Ragubeer Nasheen¹,Ratsaka Molala¹,Walwyn David R.¹,Brady Dean¹

Affiliation:

1. CSIR Biosciences, Ardeer Road, Modderfontein, South Africa 1645, and ARVIR Technologies (Pty) Ltd. Postnet Suite 300, Private Bag X30500, Houghton, South Africa 2041

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/op100208x

Reference29 articles.

1. Efficient Transformation of Thymidine into 2′,3′-Didehydro-2′,3′-Dideoxy-Thymidine (D4T) Involving Opening of a 2,3′-Anhydro Derivative by Phenylselenol

2. Nucleotide synthesis. IV. Phosphorylated 3'-amino-3'-deoxythymidine and 5'-amino-5'-deoxythymidine and derivatives

3. An Efficient Synthesis of 3′-Azido-3′-deoxythymidine (AZT)

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