Design and Synthesis of α-Aryloxyphenylacetic Acid Derivatives: A Novel Class of PPARα/γ Dual Agonists with Potent Antihyperglycemic and Lipid Modulating Activity-Reference-Cited by-同舟云学术

Design and Synthesis of α-Aryloxyphenylacetic Acid Derivatives: A Novel Class of PPARα/γ Dual Agonists with Potent Antihyperglycemic and Lipid Modulating Activity

Published:2005-06-01 Issue:13 Volume:48 Page:4457-4468
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Shi Guo Q.¹,Dropinski James F.¹,McKeever Brian M.¹,Xu Shihua¹,Becker Joseph W.¹,Berger Joel P.¹,MacNaul Karen L.¹,Elbrecht Alex¹,Zhou Gaochao¹,Doebber Thomas W.¹,Wang Peiran¹,Chao Yu-Sheng¹,Forrest Mike¹,Heck James V.¹,Moller David E.¹,Jones A. Brian¹

Affiliation:

1. Departments of Medicinal Chemistry, Metabolic Disorders, Atherosclerosis and Endocrinology and Animal Pharmacology, Merck Research Laboratories, P.O Box 2000, Rahway, New Jersey 07065-0900

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0502135

Reference48 articles.

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3. Roles of PPARs in health and disease

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