Fragment-Based Discovery of Type I Inhibitors of Maternal Embryonic Leucine Zipper Kinase-Reference-Cited by-同舟云学术

Fragment-Based Discovery of Type I Inhibitors of Maternal Embryonic Leucine Zipper Kinase

Published:2014-05-23 Issue:1 Volume:6 Page:25-30
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Johnson Christopher N.¹,Berdini Valerio¹,Beke Lijs²,Bonnet Pascal²,Brehmer Dirk²,Coyle Joseph E.¹,Day Phillip J.¹,Frederickson Martyn¹,Freyne Eddy J. E.²,Gilissen Ron A. H. J.²,Hamlett Christopher C. F.¹,Howard Steven¹,Meerpoel Lieven²,McMenamin Rachel¹,Patel Sahil¹,Rees David C.¹,Sharff Andrew¹,Sommen François²,Wu Tongfei²,Linders Joannes T. M.²

Affiliation:

1. Astex Pharmaceuticals, 436 Cambridge Science Park, Milton Road, Cambridge CB4 0QA, United Kingdom

2. Janssen Research and Development, A Division of Janssen Pharmaceutica N.V., Turnhoutseweg 30, Beerse 2340 Belgium

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ml5001245

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1. Cloning and expression of a cDNA encoding a novel protein serine/threonine kinase predominantly expressed in hematopoietic cells

2. Hunting for the SNARK in metabolic disease