Neurosteroid Analogues. 16. A New Explanation for the Lack of Anesthetic Effects of Δ16-Alphaxalone and Identification of a Δ17(20) Analogue with Potent Anesthetic Activity-Reference-Cited by-同舟云学术

Neurosteroid Analogues. 16. A New Explanation for the Lack of Anesthetic Effects of Δ16-Alphaxalone and Identification of a Δ17(20) Analogue with Potent Anesthetic Activity

Published:2011-05-06 Issue:11 Volume:54 Page:3926-3934
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Stastna Eva,Krishnan Kathiresan,Manion Brad D.,Taylor Amanda,Rath Nigam P.¹,Chen Zi-Wei,Evers Alex. S.,Zorumski Charles F.,Mennerick Steven,Covey Douglas F.

Affiliation:

1. Department of Chemistry and Biochemistry, University of Missouri—St. Louis, St. Louis, Missouri 63121, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm2002487

Reference25 articles.

1. Neurosteroid binding sites on GABAA receptors

2. Neurosteroids: Endogenous allosteric modulators of GABAA receptors

3. Action of Some Steroids on the Central Nervous System of the Mouse. II. Pharmacology