VX680 Binding in Aurora A: π−π Interactions Involving the Conserved Aromatic Amino Acid of the Flexible Glycine-Rich Loop
Author:
Affiliation:
1. NORSTRUCT, Department of Chemistry, University of Tromsø, 9037 Tromsø, Norway
Publisher
American Chemical Society (ACS)
Subject
Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/jp108286r
Reference56 articles.
1. Application of a Theory of Enzyme Specificity to Protein Synthesis
2. Enzyme flexibility, solvent and ‘weak’ interactions characterize thrombin–ligand interactions: implications for drug design
3. Understanding Protein–Ligand Interactions: The Price of Protein Flexibility
4. Protein Flexibility is an Important Component of Structure-Based Drug Discovery
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