C-Terminal Residue Optimization and Fragment Merging: Discovery of a Potent Peptide-Hybrid Inhibitor of Dengue Protease-Reference-Cited by-同舟云学术

C-Terminal Residue Optimization and Fragment Merging: Discovery of a Potent Peptide-Hybrid Inhibitor of Dengue Protease

Published:2014-07-23 Issue:9 Volume:5 Page:1037-1042
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Behnam Mira A. M.¹,Nitsche Christoph¹,Vechi Sérgio M.¹²,Klein Christian D.¹

Affiliation:

1. Medicinal Chemistry, Institute of Pharmacy and Molecular Biotechnology IPMB, Heidelberg University, Im Neuenheimer Feld 364, 69120 Heidelberg, Germany

2. Federal University of Alagoas (UFAL), Campus Arapiraca, NCEx, 57309-005 Arapiraca, Alagoas, Brazil

Funder

Deutsche Forschungsgemeinschaft

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Deutscher Akademischer Austauschdienst DAAD

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ml500245v

Reference36 articles.

1. The global distribution and burden of dengue

2. Dengue More Prevalent Than Previously Thought

3. The invasive mosquito species Aedes albopictus: current knowledge and future perspectives

4. Viral Proteases as Targets for Drug Design

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