Discovery of Conformationally Constrained Tetracyclic Compounds as Potent Hepatitis C Virus NS5B RNA Polymerase Inhibitors-Reference-Cited by-同舟云学术

Discovery of Conformationally Constrained Tetracyclic Compounds as Potent Hepatitis C Virus NS5B RNA Polymerase Inhibitors

Published:2006-11-02 Issue:24 Volume:49 Page:6950-6953
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Ikegashira Kazutaka¹,Oka Takahiro¹,Hirashima Shintaro¹,Noji Satoru¹,Yamanaka Hiroshi¹,Hara Yoshinori¹,Adachi Tsuyoshi¹,Tsuruha Jun-Ichiro¹,Doi Satoki¹,Hase Yasunori¹,Noguchi Toru¹,Ando Izuru¹,Ogura Naoki¹,Ikeda Satoru¹,Hashimoto Hiromasa¹

Affiliation:

1. Central Pharmaceutical Research Institute, Japan Tobacco Inc., 1-1 Murasaki-cho, Takatsuki, Osaka 569-1125, Japan, and Pharmaceutical Frontier Research Laboratories, Japan Tobacco Inc., 1-13-2 Fukuura, Kanazawa-ku, Yokohama, Kanagawa 236-0004, Japan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0610245

Reference22 articles.

1. Hepatitis C virus (HCV) NS5A protein: role in HCV replication and resistance to interferon‐α

2. Peginterferon Alfa-2a plus Ribavirin for Chronic Hepatitis C Virus Infection

3. Non-Nucleoside Benzimidazole-Based Allosteric Inhibitors of the Hepatitis C Virus NS5B Polymerase: Inhibition of Subgenomic Hepatitis C Virus RNA Replicons in Huh-7 Cells

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