Identification of a Chemical Tool for the Orphan Nuclear Receptor FXR
Author:
Affiliation:
1. Departments of Medicinal Chemistry, Molecular Biochemistry, Molecular Endocrinology, and Metabolic Diseases, Glaxo Wellcome Research & Development, Research Triangle Park, North Carolina 27709
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm0002127
Reference21 articles.
1. The Continuing Importance of Bile Acids in Liver and Intestinal Disease
2. Bile acids and lipoprotein metabolism
3. Two 7α‐hydroxylase enzymes in bile acid biosynthesis
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