Current Status of the Research and Development of Diacylglycerol O-Acyltransferase 1 (DGAT1) Inhibitors-Reference-Cited by-同舟云学术

Current Status of the Research and Development of Diacylglycerol O-Acyltransferase 1 (DGAT1) Inhibitors

Published:2013-09-03 Issue:24 Volume:56 Page:9820-9825
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

DeVita Robert J.¹,Pinto Shirly²

Affiliation:

1. RJD Medicinal Chemistry and Drug Discovery Consulting, 332 W. Dudley Avenue, Westfield, New Jersey 07090, United States

2. Department Cardiovascular and Diabetes Discovery, Merck Research Laboratories, 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm4007033

Reference26 articles.

1. Chapter 8. Acyl-CoA: Diacylglycerol Acyltransferase-1 Inhibition as an Approach to the Treatment of Type 2 Diabetes

2. Obesity resistance and multiple mechanisms of triglyceride synthesis in mice lacking Dgat

3. Increased insulin and leptin sensitivity in mice lacking acyl CoA:diacylglycerol acyltransferase 1

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