Synthesis and Identification of [1,3,5]Triazine-pyridine Biheteroaryl as a Novel Series of Potent Cyclin-Dependent Kinase Inhibitors-Reference-Cited by-同舟云学术

Synthesis and Identification of [1,3,5]Triazine-pyridine Biheteroaryl as a Novel Series of Potent Cyclin-Dependent Kinase Inhibitors

Published:2005-05-27 Issue:14 Volume:48 Page:4535-4546
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Kuo Gee-Hong¹,DeAngelis Alan¹,Emanuel Stuart¹,Wang Aihua¹,Zhang Yan¹,Connolly Peter J.¹,Chen Xin¹,Gruninger Robert H.¹,Rugg Catherine¹,Fuentes-Pesquera Angel¹,Middleton Steven A.¹,Jolliffe Linda¹,Murray William V.¹

Affiliation:

1. Drug Discovery Division, Johnson & Johnson Pharmaceutical Research and Development, L.L.C., 1000 Route 202, P.O. Box 300, Raritan, New Jersey 08869

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm040214h

Reference61 articles.

1. G 1 Events and Regulation of Cell Proliferation

2. Oxindole-Based Inhibitors of Cyclin-Dependent Kinase 2 (CDK2): Design, Synthesis, Enzymatic Activities, and X-ray Crystallographic Analysis

3. CYCLIN-DEPENDENT KINASES: Engines, Clocks, and Microprocessors

4. Cyclins and cancer II: Cyclin D and CDK inhibitors come of age

5. Cyclin-Dependent Kinase Inhibitors: Useful Targets in Cell Cycle Regulation

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