Covalent Thiol Adducts Arising from Reactive Intermediates of Cocaine Biotransformation-Reference-Cited by-同舟云学术

Covalent Thiol Adducts Arising from Reactive Intermediates of Cocaine Biotransformation

Published:2013-10-30 Issue:11 Volume:26 Page:1755-1764
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Schneider Kevin J.¹,DeCaprio Anthony P.¹

Affiliation:

1. Department of Chemistry and Biochemistry and the International Forensic Research Institute, Florida International University, 11200 SW Eighth Street, Miami, Florida 33199, United States

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/tx4003116

Reference48 articles.

1. Structural Alert/Reactive Metabolite Concept as Applied in Medicinal Chemistry to Mitigate the Risk of Idiosyncratic Drug Toxicity: A Perspective Based on the Critical Examination of Trends in the Top 200 Drugs Marketed in the United States

2. The Metabolism of Xenobiotics to Reactive Electrophiles in Chemical Carcinogenesis and Mutagenesis: A Collaboration with Elizabeth Cavert Miller and our Associates

3. Chemical toxicology: reactive intermediates and their role in pharmacology and toxicology

4. Metabolic activation and drug toxicity

5. Structural Alerts, Reactive Metabolites, and Protein Covalent Binding: How Reliable Are These Attributes as Predictors of Drug Toxicity?

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