A Synthetic Polyphosphoinositide Headgroup Surrogate in Complex with SHIP2 Provides a Rationale for Drug Discovery-Reference-Cited by-同舟云学术

A Synthetic Polyphosphoinositide Headgroup Surrogate in Complex with SHIP2 Provides a Rationale for Drug Discovery

Published:2012-02-27 Issue:5 Volume:7 Page:822-828
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Mills Stephen J.¹,Persson Camilla,Cozier Gyles¹,Thomas Mark P.¹,Trésaugues Lionel,Erneux Christophe²,Riley Andrew M.¹,Nordlund Pär³,Potter Barry V. L.¹

Affiliation:

1. Wolfson Laboratory of Medicinal Chemistry, Department of Pharmacy and Pharmacology, University of Bath, Bath BA2 7AY, U.K.

2. Institut de Recherche Interdisciplinaire (IRIBHM), Université Libre de Bruxelles, Campus Erasme, Brussels, Belgium

3. School of Biological Sciences, Nanyang Technological University, Singapore 637551

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/cb200494d

Reference17 articles.

1. Biphenyl 2,3′,4,5′,6‐pentakisphosphate, a novel inositol polyphosphate surrogate, modulates Ca2+responses in rat hepatocytes

2. Identification of a Second SH2-Domain-Containing Protein Closely Related to the Phosphatidylinositol Polyphosphate 5-Phosphatase SHIP

3. SHIP2 (SH2 Domain-containing Inositol Phosphatase 2) SH2 Domain Negatively Controls SHIP2 Monoubiquitination in Response to Epidermal Growth Factor

4. Evidence of SHIP2 Ser132 phosphorylation, its nuclear localization and stability

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