Synthesis and Evaluation of Dopamine and Serotonin Transporter Inhibition by Oxacyclic and Carbacyclic Analogues of Methylphenidate-Reference-Cited by-同舟云学术

Synthesis and Evaluation of Dopamine and Serotonin Transporter Inhibition by Oxacyclic and Carbacyclic Analogues of Methylphenidate

Published:2003-03-11 Issue:8 Volume:46 Page:1538-1545
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Meltzer Peter C.¹,Wang Pinglang¹,Blundell Paul¹,Madras Bertha K.¹

Affiliation:

1. Organix Inc., 240 Salem Street, Woburn, Massachusetts 01801, and Department of Psychiatry, Harvard Medical School and New England Regional Primate Research Center, Southborough, Massachusetts 01772

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0205292

Reference22 articles.

1. La preparazione di piridil- e piperidil-arilacetonitrili e di alcuni prodotti di trasformazione (Parte Ia)

2. Synthesis and Pharmacology of Potential Cocaine Antagonists. 2. Structure−Activity Relationship Studies of Aromatic Ring-Substituted Methylphenidate Analogs

3. [3H]Threo-(±)-Methylphenidate Binding to 3,4-Dihydroxyphenylethylamine Uptake Sites in Corpus Striatum: Correlation with the Stimulant Properties of Ritalinic Acid Esters

4. Methylphenidate and cocaine have a similar in vivo potency to block dopamine transporters in the human brain

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