Synthesis and Complement Inhibitory Activity of B/C/D-Ring Analogues of the Fungal Metabolite 6,7-Diformyl-3‘,4‘,4a‘,5‘,6‘,7‘,8‘,8a‘-octahydro-4,6‘,7‘-trihydroxy- 2‘,5‘,5‘,8a‘-tetramethylspiro[1‘(2‘H)-naphthalene-2(3H)-benzofuran]-Reference-Cited by-同舟云学术

Synthesis and Complement Inhibitory Activity of B/C/D-Ring Analogues of the Fungal Metabolite 6,7-Diformyl-3‘,4‘,4a‘,5‘,6‘,7‘,8‘,8a‘-octahydro-4,6‘,7‘-trihydroxy- 2‘,5‘,5‘,8a‘-tetramethylspiro[1‘(2‘H)-naphthalene-2(3H)-benzofuran]

Published:2003-05-24 Issue:13 Volume:46 Page:2697-2705
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bradbury Barton J.¹,Bartyzel Piotr¹,Kaufman Teodoro S.¹,Nieto Marcelo J.¹,Sindelar Robert D.¹,Scesney Susanne M.¹,Gaumond Bruce R.¹,Marsh Henry C.¹

Affiliation:

1. Department of Medicinal Chemistry and Laboratory of Applied Drug Design and Synthesis, School of Pharmacy, The University of Mississippi, University, Mississippi 38677, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, Mississippi 38677, and Avant Immunotherapeutics, Inc., 119 Fourth Avenue, Needham, Massachusetts 02494-2725

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0204284

Reference31 articles.

1. Morgan, B. P.Complement: Clinical Aspects and Relevance to Disease; Academic Press: New York, 1990.

2. The role of complement in inflammation and phagocytosis

3. Complement evasion strategies of microorganisms

4. The role of C3 in the immune response

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